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KMID : 0356920140660040278
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Korean Journal of Anesthesiology
2014 Volume.66 No. 4 p.278 ~ p.282
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Remifentanil dose for laryngeal mask airway insertion with a single standard dose of propofol during emergency airway management in elderly patients
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Ryu Jung-Hee
Oh Ah-Young
Baek Ji-Seok
Kim Jin-Hee
Park Sang-Heon
Noh Jae-Mun
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Abstract
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Background: This study determined the dose of remifentanil to use during insertion of a Classic™ laryngeal mask airway (LMA, The Laryngeal Mask Co., Nicosia, Cyprus) in elderly patients during emergency airway management when combined with a single dose of propofol.
Methods: Patients aged 65-80 years were enrolled. Anesthesia was induced with propofol 1 mg/kg, and then a blinded dose of remifentanil was infused over 30 s after confirming the patient’s loss of consciousness. The dose of remifentanil was determined using Dixon’s up-and-down method, starting at 0.5 μg/kg (a step size of 0.1 μg/kg). Insertion of the LMA was attempted 60 s after loss of consciousness.
Results: In total, 23 patients were recruited and the mean age ± standard deviation was 72 ± 3 years. The effective dose for successful LMA insertion in 50% of the patients (ED50) was 0.20 ± 0.05 μg/kg. No patient needed more than 0.3 μg/kg.
Conclusions: Remifentanil 0.20 ± 0.05 μg/kg with propofol 1 mg/kg resulted in excellent LMA insertion in 50% of elderly patients without significant hemodynamic changes during emergency airway management.
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KEYWORD
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Aged, Laryngeal mask airway, Remifentanil
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